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Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections come with the brand name “P- COB-VIT” and belong to the class of multivitamins as well as cosmeceuticals that are primarily used to treat nutritional deficiencies along with melasma, hyperpigmentation and acne. Nutritional deficiencies occur when the body does not absorb or get enough vitamins, minerals, and antioxidants from food. Nutrient deficiency can lead to many health problems like a weak immune system, indigestion, skin problems, heart problem, eye problems and defective bone growth.

Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections contains methylcobalamin, pyridoxine and niacinamide. Methylcobalamin helps regulate body functions like cell growth, blood formation, and protein synthesis. Pyridoxine is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Niacinamide helps build keratin, a type of protein that keeps your skin firm and healthy. It also helps your skin grow a ceramide (lipid) barrier, which can, in turn, helps retain moisture. This is beneficial for all skin types, especially if you have eczema or mature skin. Collectively, this injection helps to treat nutritional diseases and enhances the overall appearance of skin and complexion.

Medical Benefits Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections

  • This injection contains Methylcobalamin (vitamin B12), pyridoxine (vitamin B6), and niacinamide (vitamin B3). Methylcobalamin regulates body functions like cell growth, blood formation, and protein synthesis. 
  • It is used in the treatment of alcoholic neuropathy, pernicious anaemia (red blood cells are not produced due to Vitamin B12 deficiency), diabetic neuropathy (nerve damage due to high blood sugar levels), and multiple sclerosis (immune system disease affecting the brain). 
  • Pyridoxine (vitamin B6) is necessary for the development of the brain, nerves, skin, and many other parts of the body.
  • Niacinamide is a form of Vitamin B3. It functions as a humectant that draws moisture from inside the cells to the surface of the skin, thereby, hydrating it. 
  • It also helps in collagen production, thereby easing the appearance of wrinkles and fine lines. 

Directions For Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections

  • Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections will be administered by a healthcare professional.
  • Do not self-administer.


  • Store in a cool and dry place.
  • Keep it away from sunlight.
  • Keep it out of reach of children.

Precautions for Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections

  • Consult your doctor before using Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections if you are pregnant or breastfeeding.
  • Consult before its prescription as this composition may interact with anti-cancer drugs (e.g. altretamine, cisplatin, arsenic trioxide), antibiotic medications (e.g. chloramphenicol), medicines used to treat high blood pressure (e.g. metoprolol), etc. 
  • This injection may cause drowsiness and dizziness occasionally, so drive only if you are alert.
  • Inform your doctor if you have liver or kidney diseases before taking it. Your doctor will recommend only if the benefits outweigh the risks.

Side Effects of Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections

  • Upset stomach
  • Diarrhoea
  • Nausea
  • Headache
  • Dizziness 
  • Dry Skin
  • Rash
  • Redness

Frequently Asked Questions (FAQs)

How can I overcome Vitamin B6 deficiency?

Vitamin B6 deficiency occurs when your body lacks adequate Pyridoxine levels. You can overcome this deficiency by including food sources rich in Pyridoxine like milk, eggs, beef, pork, chicken or turkey, fish, peanuts, soya beans, wheat germ, oats bananas. If your Vitamin B6 levels are still low, your doctor may recommend supplements.

How to treat my Vitamin B12 deficiency?

Vitamin B12 deficiency is caused when you don’t have enough Methylcobalamine levels in your body. You can include natural Vitamin B12 sources like eggs, beef, liver, chicken, trout, salmon, tuna fish, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese in your diet for treating the deficiency. If you still have low levels of B12, please consult your doctor about its supplements.

My skin type is dry. Can I use Methylcobalamin + Pyridoxine Hydrochloride + Niacinamide Injections?

This composition is suitable for all skin types. In fact, niacinamide really helps hydrate the skin.