SEIZOPAX Injection is a sterile anticonvulsant formulation containing Levetiracetam Injection IP 100 mg/ml, used for the treatment and management of various types of seizures in patients with epilepsy. Levetiracetam is a modern antiepileptic medication that helps control abnormal electrical activity in the brain, thereby reducing the frequency and severity of seizures.

SEIZOPAX Injection is primarily used when oral administration is temporarily not feasible, such as in hospitalized patients, emergency situations, post-surgical care, or patients unable to swallow oral medications. It provides rapid therapeutic levels and effective seizure control under medical supervision.

Composition of the SEIZOPAX Injection

Active Ingredient

Levetiracetam IP – 100 mg/ml

Dosage Form

• Sterile Injection
• Intravenous (IV) Administration

Therapeutic Category

• Antiepileptic Drug (AED)
• Anticonvulsant Medication
• Neurological Therapy

How Levetiracetam Injection Works

Levetiracetam belongs to a newer generation of antiepileptic medications.

Mechanism of Action

Levetiracetam works by binding to a specific protein known as Synaptic Vesicle Protein 2A (SV2A) in the brain.

This action helps to:

• Stabilise abnormal electrical activity in the brain.
• Reduce excessive neuronal firing.
• Prevent the spread of seizure activity.
• Improve seizure control.
• Protect nerve cells from excessive excitation.

Unlike many traditional antiepileptic drugs, Levetiracetam has a unique mechanism of action and generally demonstrates fewer drug interactions.

Indications Levetiracetam injection

SEIZOPAX Injection is indicated for the treatment and management of:

Epilepsy

• Partial-Onset Seizures
• Focal Seizures
• Generalized Tonic-Clonic Seizures
• Myoclonic Seizures

Hospital-Based Seizure Management

• Patients unable to take oral medications 
• Temporary replacement of oral Levetiracetam therapy
• Post-operative seizure control
• Emergency seizure management under physician supervision

Neurological Conditions

• Seizure disorders requiring intravenous antiepileptic therapy
• Adjunctive treatment in epilepsy management

Benefits of Levetiracetam Injection

Here are some of the top benefits of the Levetiracetam injections : 

• Effective Seizure Control; Helps reduce the frequency and severity of seizures in patients with epilepsy.
• Rapid Therapeutic Action: Intravenous administration provides quick achievement of therapeutic drug levels.
• Suitable Alternative to Oral Therapy: Useful when oral administration is temporarily not possible.
• Broad Spectrum Antiepileptic Activity: Effective against multiple seizure types.
• Minimal Drug Interactions: Compared to several older antiepileptic medications, Levetiracetam generally has fewer clinically significant drug interactions.
• Well-Tolerated Treatment Option: Widely used due to its favourable safety and tolerability profile.
• Supports Long-Term Epilepsy Management: Can be transitioned to oral therapy when clinically appropriate.

Indications by Seizure Type

Here are some of the indications of using Levetiracetam injection 

Partial-Onset Seizures

Helps control seizures originating in a specific area of the brain.

Generalised Tonic-Clonic Seizures

Assists in preventing widespread seizure activity involving the entire brain.

Myoclonic Seizures

Reduces sudden involuntary muscle jerks associated with epilepsy.

Refractory Seizure Disorders

May be used as part of combination antiepileptic therapy under specialist supervision.

Recommended Dosage

The dosage of SEIZOPAX Injection should be determined solely by a qualified healthcare professional.

Administration Guidelines

• Administered intravenously by trained healthcare personnel.
• Dose depends on patient age, body weight, medical condition, and seizure type.
• Infusion rate and duration should follow physician recommendations.
• Transition to oral Levetiracetam may occur when appropriate.

Important

• Do not self-administer.
• Use only under medical supervision.
• Follow hospital administration protocols.

Possible Side Effects

Like all medicines, Levetiracetam Injection may cause side effects in some individuals.

Common Side Effects

• Drowsiness
• Fatigue
• Dizziness
• Headache
• Weakness
• Sleepiness
• Irritability

Less Common Side Effects

• Mood changes
• Anxiety
• Agitation
• Loss of appetite
• Nausea
• Vomiting

Serious Side Effects

Seek immediate medical attention if any of the following occur:

• Severe allergic reactions
• Difficulty breathing
• Swelling of the face, lips, or throat
• Severe behavioral changes
• Depression or suicidal thoughts
• Severe skin reactions

Warnings and Precautions

Consult Your Doctor Before Use If You:

• Have kidney disease.
• Have a history of depression or psychiatric illness.
• Have previously experienced severe allergic reactions to antiepileptic medicines.
• Have liver impairment.

Pregnancy

Levetiracetam may be used during pregnancy only if clearly needed and prescribed by a healthcare professional after careful risk-benefit assessment.

Breastfeeding

Levetiracetam may pass into breast milk. Consult your physician before use while breastfeeding.

Driving and Machinery

After transitioning to oral therapy, avoid driving or operating machinery until you know how the medicine affects you.

Drug Interactions

Levetiracetam generally has fewer drug interactions than many traditional antiepileptic drugs.

However, inform your doctor if you are taking:

• Other antiepileptic medications
• Sedatives
• Sleeping pills
• Antidepressants
• Anti-anxiety medications
• Central nervous system depressants

Medical supervision is essential when combining therapies.

Overdose Information

Symptoms of overdose may include:

• Extreme drowsiness
• Agitation
• Reduced consciousness
• Respiratory depression
• Severe weakness

Seek immediate emergency medical care in case of suspected overdose.

Storage Instructions

To maintain product quality and sterility:

Store

• Below 25°C or as directed on the product label.
• In a cool and dry place.

Protect From

• Direct sunlight.
• Excessive heat.
• Freezing temperatures.

Keep

• In the original packaging until use.
• Out of reach of children.

Do Not Use

• If the solution appears discolored or contains particles.
• After the expiry date mentioned on the package.

Packaging Information

• Dosage Form: Sterile Intravenous Injection
• Strength: Levetiracetam IP 100 mg/ml
• Packed in pharmaceutical-grade vials/ampoules to ensure sterility, stability, and safety.